What Vaccines Do South Africans Need for Zambia in 2026?

Quick answer: South African citizens travelling directly from South Africa to Zambia generally do not need a yellow fever vaccination certificate because Zambia is not on the WHO list of countries with yellow fever transmission risk. However, Zambia requires proof from travellers aged one year or older arriving from a yellow-fever-risk country, including travellers who have transited for more than 12 hours through an airport in such a country.

For health protection, unvaccinated travellers aged one year or older should generally receive hepatitis A vaccination for Zambia, while routine vaccinations should be reviewed before departure. Malaria prevention is also important because malaria is identified as a health risk in Zambia; a clinician should assess your itinerary and medical history before recommending any preventative medicine.

Last checked August 2026 — always confirm with official sources before travelling.

Yellow fever certificate rules for South Africans travelling to Zambia

Yellow fever is the main vaccination-related entry issue for a Zambia itinerary. The requirement is based on your travel history and transit route, not simply on holding a South African passport. Travellers arriving from a country with risk of yellow fever virus transmission must generally show an International Certificate of Vaccination or Prophylaxis (ICVP) if they are aged one year or older. A transit or layover lasting more than 12 hours through an airport in a risk country can also trigger the requirement.

Itinerary	What the research indicates
South Africa directly to Zambia, with no relevant transit	A yellow fever certificate is generally not required under the cited Zambia entry rule because South Africa and Zambia are not listed as yellow-fever-risk countries in the relevant CDC/WHO information.
Arriving in Zambia from a yellow-fever-risk country	Travellers aged one year or older should expect to provide proof of vaccination.
Transiting for more than 12 hours through an airport in a yellow-fever-risk country	A certificate may be required on arrival in Zambia. Check the complete itinerary with the airline and official authorities.
Returning to South Africa from Zambia	South Africa’s published government information says travellers coming from Zambia no longer need to produce a yellow fever certificate because Zambia is classified among countries with low potential for exposure.

The CDC’s country information states that yellow fever vaccination is generally not recommended for travel to Zambia’s North-Western or Western provinces and is not recommended for the other areas listed in its country guidance. This is a health recommendation, separate from an entry-document requirement. A traveller may therefore need to consider itinerary-specific medical advice even when a certificate is not required for entry.

When a yellow fever vaccine is required, the South African High Commission states that it must be WHO-approved, administered at an approved yellow fever vaccination centre and given at least 10 days before departure to South Africa. The same source states that the certificate provides lifetime validity. Carry the original ICVP with your passport and check whether every transit point changes the certificate requirement before you leave.

Medical exemptions are handled differently from ordinary missing documentation. South African government guidance refers to travellers holding a medical exemption certificate and says that additional health-monitoring measures may apply. If you cannot receive yellow fever vaccine for medical reasons, obtain advice from an approved vaccination centre and confirm the border procedure before travelling.

Recommended vaccinations for Zambia and when to get them

There is no single vaccination schedule that applies to every safari traveller. Your recommended vaccines depend on your existing records, age, health conditions, pregnancy status, length of stay, accommodation, activities and route. The South African Department of International Relations and Cooperation advises South African citizens to make enquiries about health risks and prescribed immunisations before travelling, and to consult a doctor when they have a history of health challenges.

Hepatitis A

Hepatitis A vaccination is generally recommended for unvaccinated travellers aged one year or older going to Zambia. Infants aged six to 11 months should also be vaccinated in the circumstances described by the CDC, but that early dose does not count towards the routine two-dose series.

If a traveller is allergic to a vaccine component, the CDC states that a single dose of immune globulin can provide protection for up to two months, depending on the dosage. Travellers over 40, immunocompromised travellers and people with chronic medical conditions who will leave for a risk area in less than two weeks may be advised to receive the initial vaccine dose and immune globulin at the same appointment. These decisions require a qualified clinician.

Routine vaccinations

Before Zambia travel, ask a healthcare professional to review your routine vaccinations and whether any are due under South Africa’s age-appropriate schedule. DIRCO specifically advises travellers to obtain information about prescribed immunisations and medication before departure. Take your vaccination record to the consultation so the clinician can identify missing or outdated doses rather than repeating vaccines unnecessarily.

Hepatitis B, typhoid and other itinerary-based vaccines

Additional vaccines may be considered according to personal risk and the nature of the trip. Travel-health guidance for Zambia identifies hepatitis B, typhoid and rabies among vaccines that may be discussed, while noting that recommendations depend on the traveller and itinerary. This can be relevant for longer stays, close contact with local communities, healthcare-related exposure, animal contact or travel away from established tourist routes.

Do not treat a safari package as proof that a vaccine is compulsory. A private lodge, national park or wildlife safari park does not replace a medical assessment, and the yellow fever certificate rule is determined by the route into Zambia. Travellers comparing safari packages on SafariFind should check the full transport itinerary, including regional connections and airport transits, before booking appointments.

For comparison, SafariFind also publishes guidance on vaccines for Emiratis travelling to Zambia and Zambia health rules for Singaporean travellers; the same destination can have different entry-document implications depending on the departure country and transit route.

Malaria in Zambia: risk areas, prophylaxis and prevention

Malaria is listed among the health risks travellers may face in Zambia. The UK government advises travellers to check vaccine recommendations and health risks before departure, specifically including malaria. The research supplied for this article does not establish a single malaria-free region or a universal medicine for every Zambia itinerary, so do not assume that a short safari, a city stay or travel during a particular season removes the risk.

Arrange an itinerary-specific consultation with a doctor or travel-health clinic. Discuss the provinces and accommodation types you will visit, the dates of travel, previous reactions to medicines, pregnancy or plans for pregnancy, allergies, chronic conditions and any regular medication. A clinician can decide whether malaria prophylaxis is appropriate and which option suits your circumstances; the research does not support naming one medicine or dosage as correct for all South African travellers.

Medication is only one part of malaria prevention. Ask your clinician or pharmacist about practical mosquito-avoidance measures suitable for Zambia, such as repellent, clothing and sleeping arrangements. Seek medical attention promptly if you become unwell during the trip or after returning and mention that you have travelled to Zambia. The cited government health guidance identifies malaria as a risk but does not provide a universal symptom threshold or emergency protocol for every traveller.

Health documents and travel insurance

Carry your passport, vaccination record and, where applicable, the original yellow fever ICVP. Check the entire route rather than only the first flight: a long transit through a yellow-fever-risk country can affect Zambia’s certificate requirement. The CDC also advises that the full travel itinerary should be considered because airport transfers and long layovers can affect how entry rules are applied.

Travel insurance should cover medical treatment and unexpected medical evacuation. The UK government advises travellers to check that Zambia can provide the healthcare they may need and to obtain appropriate insurance for local treatment or evacuation, particularly when travelling with a health condition or during pregnancy.

Healthcare standards and availability can vary substantially outside major centres. The UK government states that medical facilities throughout Zambia are below UK standards, rural facilities are basic and emergency services are limited. It recommends adequate insurance, accessible funds for treatment and repatriation, and carrying basic medical supplies.

South African citizens should also review the latest advice from DIRCO and the South African Department of Health before departure. DIRCO directs travellers to make timeous enquiries about health risks and vaccination requirements and provides Department of Health contact details for international health requirements.

Medication rules and what to pack

Ask your prescribing doctor how to manage regular medicines during the trip and pack enough for the planned stay, allowing for delays. Keep medicines in their original packaging and carry a copy of the prescription or a doctor’s letter where appropriate; confirm any Zambia import restrictions for your specific medicine with the relevant Zambian authority before departure. The supplied official research does not provide a complete list of permitted or restricted medicines, so confirm rather than relying on a general packing list.

A practical health kit can include the medicines you normally use, basic first-aid supplies, sun protection, insect-repellent products and any items recommended by your clinician. The UK government specifically advises travellers to carry basic medical supplies because rural healthcare facilities may be basic and emergency services limited.

Do not pack prescription medication for another person or use antimalarial medicine prescribed for someone else. Your doctor needs to consider your health history and possible medicine interactions. If you are pregnant, immunocompromised, have a chronic medical condition or have previously reacted to a vaccine or antimalarial, arrange professional advice before booking vaccinations.

Health facilities and emergencies in Zambia

Healthcare access is generally more limited in rural parts of Zambia than in major urban centres, according to the UK government’s travel-health guidance. Emergency services may also be limited, so confirm how your lodge, camp or tour operator would arrange transport to medical care before travelling into remote safari areas.

Save your insurer’s emergency-assistance number offline and keep your policy details accessible. Ask your accommodation provider for the nearest suitable medical facility and the local emergency procedure on arrival. If you need treatment, tell the clinician about your itinerary, recent vaccines, regular medicines and any possible mosquito exposure.

Before travelling, make a simple plan: book a travel-health consultation, review routine vaccines, assess hepatitis A and itinerary-based vaccination needs, check the yellow fever rule against every transit point, discuss malaria prevention and purchase appropriate insurance. Requirements can change after this article is published, so verify the final position with Zambia’s official authorities, your airline, the South African Department of Health or DIRCO, and an approved vaccination centre.

Frequently Asked Questions

Do South African citizens need a yellow fever vaccine for Zambia?

South African citizens travelling directly from South Africa generally do not need a yellow fever certificate for Zambia. Zambia requires proof from travellers aged one year or older arriving from a yellow-fever-risk country or transiting for more than 12 hours through an airport in one.

Does a transit airport affect Zambia’s yellow fever requirement?

Yes. A transit or layover of more than 12 hours through an airport in a country with yellow fever transmission risk can trigger Zambia’s certificate requirement for travellers aged one year or older. Check the complete itinerary with the airline and official authorities.

Is yellow fever vaccination recommended for a Zambia safari?

The CDC states that yellow fever vaccination is generally not recommended for Zambia’s North-Western or Western provinces and is not recommended for the other areas covered by its country guidance. Entry requirements and personal medical recommendations are separate questions, so discuss your exact route with a clinician.

Is hepatitis A vaccination recommended for Zambia?

Yes, the CDC generally recommends hepatitis A vaccination for unvaccinated travellers aged one year or older going to Zambia. Infants aged six to 11 months may also need an early dose in the circumstances described by the CDC, and that dose does not count towards the routine two-dose series.

How far in advance should South Africans get Zambia travel vaccines?

Book a travel-health consultation as early as possible so a clinician can review routine and itinerary-based vaccines, malaria prevention and your medical history. The supplied research does not establish one universal lead time for every vaccine or traveller, so confirm the schedule with an approved vaccination centre.

Do South Africans need malaria tablets for Zambia?

A clinician should assess whether malaria prophylaxis is appropriate for your specific Zambia itinerary and health circumstances. Malaria is identified as a health risk in Zambia, but the supplied research does not support one medicine or dosage for every traveller.

What health documents should I carry to Zambia?

Carry your passport, vaccination record and, if your route requires it, the original yellow fever International Certificate of Vaccination or Prophylaxis. Review every transit point because a long layover in a yellow-fever-risk country can affect the requirement.

Does South Africa require a yellow fever certificate when returning from Zambia?

South African government information says travellers coming from Zambia no longer need to produce a yellow fever certificate because Zambia is included among countries with low potential for exposure to yellow fever. Recheck the current rule before return travel.

What medical care is available in rural Zambia?

Rural facilities in Zambia may be basic and emergency services limited. The UK government advises travellers to carry basic medical supplies, have suitable travel insurance and keep accessible funds for treatment and repatriation.

Can I travel to Zambia if I cannot have the yellow fever vaccine?

You may need a medical exemption certificate and should confirm the border procedure before travelling. South African government guidance says travellers with medical exemptions may be allowed entry but can be subject to health reporting or surveillance measures.